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Flomax (Tamsulosin) is an alpha-blocker that is used to improve symptoms, associated with an enlarged prostate. Flomax is an alpha-blocker. It works by relaxing muscles in the prostate and bladder, which helps to improve urine flow and reduce symptoms of BPH.
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In the titration studies (n=644) (with most patients eventually receiving 100 mg), results were similar 60 Caps Extendaquin 2 Bottles Daily For 30 Days. (1997) 255 Funding source: NR N screened = NR N randomized = 69 IG screened = NR IG randomized = 32 CG screened = NR CG randomized = 37 Inclusion: ED Exclusion: severe kidney or liver disorders, pts using anti-hypertensives or other drugs (especially alpha or beta blocking agents) Age, mean (range): IG 54(26-80), CG 55(3981) Race (%): Co-morbidities (unrelated to disease): NR Blood glucose (or HbA1C)(%): NR Previous ED treatment (N): self-injections IG 5, CG 16; psychotherapy IG 1, CG 0; vacuum device IG 1, CG 1 BMI (kg|m2): NR Smoking status: NR Initial body weight: NR Other: NA Concomitant medications: NR Duration of ED (yr): NR Underlying disease (diagnosis) (N or % of diseased|grp): ED 69(100) Psychogenic ED (N): IG 16, CG 20 Physiologic ED (N): vascular IG 5, CG 5; diabetes IG 5, CG 7; neurogenic IG 1, CG 0; peyronies disease IG 1, CG 1; Mixed|unknown ED: IG 4, CG 4 Other: NA IG: trazodone, oral CG: placebo, oral IG: Dose: 50 mg Duration: 4 or 6 wks Frequency: X3|d = 150 mg Compliance (%): NR CG: Dose: 50 mg Duration: 4 or 6 wks Frequency: X3|d = 150 mg Compliance (%): NR Run In period: 2 wks Wash out period: NA F|u duration (both on and off treatment): NA Other: NA Primary outcome results: Patients diary: NR in results Questionnaire (N [%]): medication did not work IG 15(58), CG 20(62); it works, but insufficiently IG 6(23), CG 6(19); it works, but too many side-effects IG 1(4), CG 1(3); medication works well IG 4(15), CG 5(16) = [p> 0 Flomax 60 Caps. Moreover, a statistically significant higher incidence of these events was reported across several trials in tadalafil versus placebo arms Do U Need A Prescription Flomax 30 0.4 Mg 64.07$. 9-29) yr Underlying disease: NR Psychogenic ED: NR Physiologic ED: NR Mixed ED: NR IG: Sildenafil CG: placebo IG: Dose: 50 mg (32%); titrated up to 100 (64%), or down to 25 mg (4%) based on patient response & tolerability Duration: 12 wks Frequency: max once | d, 1 hr before sexual activity Compliance (%): NR CG: Dose: NA Duration: as IG Frequency: as IG Compliance (%): NR Run In period: 4 wks Wash out period: NA F|u duration: 12 wks Note: this trial was followed by an open label period of 24-48 wks (n=206) & included those with non tx related AE; (50 mg sildenafil) Primary outcome results:IIEF-Q1 (improvement in erection), % of pts: 90% vs.
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5,316,321,322,325,329 There was adequate description of study withdrawals, drop-outs by treatment group in eight trials. Such agents may increase blood levels of PDE5 inhibitors, so that lower doses of PDE5 inhibitors are necessary.































